这两个连词都可用于让步结构，但两者所连接的句子的主从关系恰好相反。
比较:
Although it looks like a huge monster，that country is in essence a paper tiger.
虽然看起来像个庞然大物，那个国家在本质上却是一只纸老虎。
While it is in essence a paper tiger，that country looks like a huge monster.
尽管本质上是只纸老虎，那个国家看起来倒像个庞然大物。