这位网友问：“这句话的语法有问题吗？”

【答】是的，有3个小的问题，改正如下：

The human genome contains 3 x 109 base pairs of nucleotides, including 140000 genes. If any one of these genes mutates, it may lead to its coding protein structure and function unusual, and also cause a kind of important disease, genetic disease.

红色为修改的部分。此外，109应为10的9次方。